This is because women’s bodies generally have less water than men’s bodies. Because alcohol mixes with body water, a given amount of alcohol is more concentrated in a woman’s body than in a man’s. As a result, women are more susceptible to alcohol-related damage to organs such as the liver. This pamphlet lists medications that can cause harm when taken with alcohol and describes the effects that can result. The list gives the brand name by which each medicine is commonly known na vs aa (for example, Benadryl®) and its generic name or active ingredient (in Benadryl®, this is diphenhydramine). The list presented here does not include all the medicines that may interact harmfully with alcohol.
Checking alcohol-medication interactions
- In addition, evidence supporting CBD’s efficacy in treating psychiatric disorders remain scarce26.
- Several muscle relaxants (e.g., carisoprodol, cyclobenzaprine, and baclofen), when taken with alcohol, may produce a certain narcotic-like reaction that includes extreme weakness, dizziness, agitation, euphoria, and confusion.
- Both of these beta-lactams have the ability to upregulate glutamate transporter-1 and phosphorylated-AKT levels, which are responsible for mediating the brain reward center for alcohol intake (12).
- This patient reportedly experienced symptoms following consumption of 500 mg of griseofulvin and a single can of beer.
- Another combination drug called phentermine/topiramate (Qsymia) is approved for weight loss in adults and in children ages 12 years and older with obesity.
Taking these medications together could increase your risk of side effects from Contrave. People with depression are at increased risk of substance abuse and addiction. If you’re finding it hard to stop drinking and are concerned about your alcohol use, there are many forms of help out there. In addition to substance abuse counseling and treatment programs, there are many support groups including Alcoholics Anonymous and newer, online communities. Conversely, people taking MAO inhibitors or atypical antidepressants can experience adverse consequences when simultaneously consuming alcohol.
Conversely, in people who chronically drink alcohol, long-term alcohol consumption activates cytochrome P450 and, consequently, warfarin metabolism. As a result, warfarin is broken down faster than normal, and higher warfarin doses are required to achieve the desired anticoagulant effect. Thus, alcohol consumption can result in dangerously high or insufficient warfarin activity, depending on the patient’s drinking pattern. Therefore, patients taking warfarin generally should avoid alcohol.
Consider an increase in CBD dosage (based on clinical response and tolerability) when co-administered with a strong CYP3A4 inducer. Will decrease the level or effect of CBD by affecting hepatic/intestinal enzyme CYP3A4/CYP2C19 metabolism. Will decrease the level or effect of CBD by affecting hepatic/intestinal enzyme CYP3A4 metabolism or CYP2C19 metabolism. Pyrazinamide is another agent used in combination therapy for the treatment of TB (116). Ethionamide is used in the treatment of TB that is resistant to first-line agents (113). Ethambutol is used in combination with other antimycobacterials as first-line therapy for treatment of tuberculosis (112).
Administration
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. SSRIs (i.e., fluvoxamine, fluoxetine, paroxetine, and sertraline), which are currently the most widely used anti-depressants, are much less sedating than are TCAs. In addition, no serious interactions appear to occur when these agents are consumed with moderate alcohol doses (Matilla 1990). In fact, SSRIs have the best safety profile of all antidepressants, even when combined in large quantities with alcohol (e.g., in suicide and overdose situations).
Nortriptyline, oral capsule Images
If you have certain risk factors related to seizures, your doctor will likely not prescribe Contrave for you. These factors include if you take another drug that increases your risk of seizures or if you have a seizure disorder or a condition that may cause seizures. This is because Contrave may cause seizures as the dose increases. No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal.
Given few existing case reports or clinical trials available on CBD’s interactions with other drugs, future research should address and characterize the mechanisms of these interactions. The growing popularity of CBD use and the lack of sufficient information on CBD drug–drug interactions make it imperative that we investigate the impact of CBD upon concomitant drug use in future randomized, controlled trials. TCAs with a higher ratio of sedative-to-stimulant activity (i.e., amitriptyline, doxepin, maprotiline, and trimipramine) will cause the most sedation.
